Use of iohexol to quantify hemodialysis delivered and residual renal function.

Plasma clearance of iohexol in hemodialysis patients requires prolonged blood sampling. that delaying collection of a late plasma sample may allow better estimation of plasma clearance of iohexol (CL iohexol) in patients with low glomerular filtration rates (GFRs).

METHODS: Ten hemodialysis (HD) patients were evaluated. However, a late sample is not always feasible, for example, in patients treated with peritoneal dialysis (7 days per week) or frequent hemodialysis (4-7 days per week). Furthermore, relatively little is known about extrarenal CLiohexol in humans, including its source (presumably hepatic), variability, and dependence on serum iohexol concentrations. 1996-01-01 · The renal clearance of iohexol was evaluated as an alternative method for RRF assessment (iohexol-derived RRF) in hemodialysis patients. An intravenous bolus of iohexol (12 ml; 300 Residual renal function (RRF) may contribute significantly to the total dialysis prescription. Conventional quantitation of RRF in hemodialysis (HD) patients is measured Request PDF | On May 1, 2016, Gunnar Sterner and others published Plasma Clearance of Iohexol in Hemodialysis Patients Requires Prolonged Blood Sampling | Find, read and cite all the research you Use of iohexol to quantify hemodialysis delivered and residual renal function.

CONCLUSION: Iohexol clearance is a valid method for measuring GFR in patients at any stages of renal failure. Elimination rate and clearance of the contrast media were measured as indices of their dialyzability. RESULTS: After 4 hours of hemodialysis, 78.4+/-6.5% of iohexol and 72.4+/-6.0% ioxaglate were eliminated. Clearance of iohexol was higher than that of ioxaglate at all sampling times.

Dialysis and Transplantation, ISSN 0931-0509, E-ISSN 1460-2385, Vol. GFR determination in adults with a single-sample iohexol plasma clearance

No severe hemodynamic change nor adverse reaction were observed. First studies in humans documenting biochemical properties and pharmacokinetics parameters (15-18) showed that iohexol is excreted unchanged in urine and its renal clearance is almost identical to 51 Cr-EDTA clearance. The reliability of GFR determination by iohexol plasma clearance was demonstrated a few years later by Krutzén et al.

Determination of residual renal function with iohexol clearance in hemodialysis patients. Kidney Int, 49 (1996), pp. 232-235.

This page in English. Författare: Gunnar Sterner trycket renalt clearance för mätning av njurarnas utsönd- ringsfunktion av olika ance och plasmaclearance för iohexol vid undersökning av patienter med Assessing residual renal function and efficiency of hemodialysis – an application for ERA-EDTA. European Renal Association – European Dialysis and Transplant Haraldsson B: Improved clearance of iohexol with longer haemodialysis despite. inulin clearance or.

Residual renal function (RRF) may contribute significantly to the total dialysis prescription. Conventional quantitation of RRF in hemodialysis (HD) patients is measured by urea clearance and requires a 24-hour urine collection which is often difficult to perform and inaccurate. The renal clearance of Use of iohexol to quantify hemodialysis delivered and residual renal function. This result agrees with data from anuric patients for whom extrarenal iohexol clearance was measured between 2 hemodialysis sessions. Thus, we believe that properly performed plasma iohexol clearance using long sampling time is a suitable technique for estimating residual kidney function in patients receiving hemodialysis. Determination of residual renal function with iohexol clearance in hemodialysis patients. Author links open overlay panel Suzanne K. Swan 1 Charles E. Halstenson 1 Bertram L. All clearance measurements are reported in mL/min/1.73 m 2, and median [IQR] values were as follows: 24-hour plasma CL iohexol, 7.1 [5.3-9.4]; 4-hour plasma CL iohexol, 12.7 [7.8-18.0]; 24-hour urinary CL iohexol, 2.3 [0.5-4.3]; and 24-hour urinary CL urea,cr, 3.2 [1.6-5.4].
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An intravenous bolus of iohexol (12 ml; 300 mg iodine/ml) was administered to 42 hemodialysis patients following routine HD. extrarenal iohexol clearance was measured between 2 hemodial-ysis sessions.3,4 Thus, we believe that properly performed plasma iohexol clearance using long sampling time is a suitable technique for estimating residual kidney function in patients receiving hemodi-alysis.

Comparison of iohexol and 51Cr-EDTA clearances 1177. 26 Sep 2018 Plasma clearance of iohexol for renal function determination has a on peritoneal dialysis, as well kidney transplant recipients and living 17 May 2018 method for measuring GFR by plasma clearance of iohexol, a non-ionic toneal dialysis (0.3%), 738 (25.5%) kidney transplant re- cipients The patient told us that he had good diuresis and therefore a measurement of kidney function was performed.
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Residual renal function (RRF) may contribute significantly to the total dialysis prescription. Conventional quantitation of RRF in hemodialysis (HD) patients is

232-235.

The patient told us that he had good diuresis and therefore a measurement of kidney function was performed. A 48-hour iohexol clearance measurement showed

I dessa fall uttrycks mätresultat för S-Iohexol i mg/L, och ej i mL/min/1,73m 2 (beräknat clearance) i journalsystemet. Iohexol-clearance används för bedömning av njurarnas filtrationsförmåga (GFR). På remissen ska anges om beställningen avser enbart iohexolkoncentration eller beräkning av iohexol-clearance (GFR). Analys av iohexol och beräkning av iohexol-clearance (GFR) utförs av Klinisk kemi SU/Sahlgrenska. Use of iohexol to quantify hemodialysis delivered and residual renal function.

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